N′-Cyclododecylidenepyridine-4-carbohydrazide

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N′-Cyclo­dodecyl­idene­pyridine-4-carbohydrazide

The title compound, C(18)H(27)N(3)O, is a derivative of the anti-tuberculosis drug isoniazid (systematic name: pyridine-4-carbohydrazidei). The crystal structure consists of repeating C(4) chains along the b axis, formed by N-H⋯O hydrogen bonds with adjacent amide functional groups that are related by a b-glide plane. The cyclo-dodecyl ring has the same approximately 'square' conformation, as s...

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N′-(4-Methyl­benzyl­idene)thio­phene-2-carbohydrazide

In the title compound, C(13)H(12)N(2)OS, the dihedral angle between the aromatic rings is 14.84 (17)°. In the crystal, inversion dimers linked by pairs of N-H⋯O hydrogen bonds generate R(2) (2)(8) loops.

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N′-(4-Cyano­benzyl­idene)thio­phene-2-carbohydrazide

The title compound, C(13)H(9)N(3)OS, was prepared by the reaction of thio-phene-2-carbohydrazide and 4-formyl-benzonitrile. The dihedral angle between the benzene and thio-phene rings is 11.9 (1)°. In the crystal structure, mol-ecules are linked into centrosymmetric dimers by pairs of N-H⋯O hydrogen bonds.

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N′-(4-Hy­droxy­benzyl­idene)thio­phene-2-carbohydrazide

In the title compound, C(12)H(10)N(2)O(2)S, the dihedral angle between the benzene and thio-phene rings is 23.34 (16)°. In the crystal structure, mol-ecules are linked by N-H⋯O and O-H⋯O hydrogen bonds, forming (100) sheets.

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N′-(4-Bromo­benzyl­idene)thio­phene-2-carbohydrazide

In the title compound, C(12)H(9)BrN(2)OS, the dihedral angle between the aromatic rings is 10.0 (2)°. In the crystal structure, inversion dimers linked by pairs of N-H⋯O hydrogen bonds occur, generating R(2) (2)(8) loops. Weak aromatic π-π stacking [centroid-centroid separations = 3.825 (3) and 3.866 (3) Å] also occurs.

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2012

ISSN: 1600-5368

DOI: 10.1107/s1600536812011774